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WHAT IS INTERMITTENT HYPOXIC?

Severe hypoxia is well known to be associated with deleterious consequences for the human body.

For example, obstructive sleep apnea with brief and frequently recurrent cycles of hypoxia has been found to be linked to hypertension, stroke, and adverse cardiac events.

On the contrary, short and controlled intervals of moderate hypoxia that is no less than 9% cause a type of moderate stress that leads to beneficial adaptations, including but not limited to:

• Increase of vasolidation, angiogenesis, erythropoiesis
• Induction of defence protein synthesis (HSP, Fe-RP, repair enzymes)
• Increase of glycolic enzymes
• Improvement of insulin sensitivity
 Decrease of cholesterol levels
• Anti-intlammatory effect

WHAT IS THE INTERMITTENT HYPOXIC THERAPY?

It involves breathing in hypoxic (low oxygen) air with intervals of hyperoxic (high oxygen) air. Normoxic (normal oxygen concentration) phases can replace the hyperoxic phases, but are generally less efficient, since the restoration of the normal SpO, levels takes longer and the effect of the succesive hypoxic phase is decreased spalt.

The patient quietly inhales the air mixture supplied by the precisely controlled unit through a mask, and remains lying down on a comfortable position for the whole duration of the therapy. Not rarely, will the patient fall asleep and describe the whole procedure as deeply relaxing.

MITOCHONDRIA

Under the conditions of hypoxia, mitochondrial respiratory chain is the main intracellular source of reactive oxygen species (ROS) generation. Excessive formation of ROS can potentially disturb normal metabolic processes, the structure of proteins, and mitochondrial genome.

In most of cases of severe hypoxia, a mitochondrial dysfunction is the major component of most pathological processes that appear.

On the other hand, it has been proved that adaptation to interval hypoxic stimulation causes positive changes in the mitochondrial apparatus of the cells, explaining the positive effects on the body.

Specifically, there is a restructurization of the tissue energy as the human organism implements a more economical use of oxygen.

The mechanisms of adaptation to intermittent hypoxia enable the body not only to survive in conditions of acute shortage of oxygen, but also increase body resistance to emotional stress, intense exercise, and other type of stress.

INTERMITTENT HYPOXIC TRAINING (HT) IMPLEMENTS ITS ANT-HYPOXIC EFFECT BY STIMULATING ITS OWN ENDOGENOUS DEFENSE MECHANISMS AT ALL LEVELS – FROM GENES TO THE WHOLE ORGAN OR TISSUE.

IHT significantly improves the control of mitochondrial quality, which is regulated by the balance between the biogenesis -the birth of new and autophagic destruction -the death of old mitochondria. In simpler words, self-imposed quality control is achieved by the establishment of a fine balance between the elimination of damaged and dysfunctional mitochondria and the generation of new and “healthy”. mitochondria.

HOW IMPORTANT ARE HEALTHY MITOCHONDRIA?

Mitochondrial dysfunction occurs when the mitochondria do not work as well as they should. Many conditions can lead to secondary mitochondrial dysfunction and affect other diseases, including Alzheimer’s disease, muscular dystrophy. Lou Gehrig’s disease, diabetes and cancer.One in 5,000 individuals has a genetic mitochondrial disease.

Each year, about 1,000 to 4,000 children in the United States are born with a mitochondrial disease.

With the number and type of symptoms and organ systems involved, mitochondrial diseases are often mistaken for other, more common diseases. Symptoms of mitochondrial diseases depend on which cells of the body are affected.

Patients symptoms can range from mild to severe.

SPORTS

It has been shown that cell training with IHT can improve the cardiopulmonary efficiency and lactate removal, Also, It restores performance levels in athletes with overtraining syndrome.

The technology is already popular among elite athletes as a legal way to improve performance.

INDUSTRIAL HEALTH

Studies have concluded that IHT can be used as a preventive therapy for professionals dealing with harmful substances. Research has shown that it caused significant improvements in the respiratory system and in the feeling of well-being in populations working in an aggravating for the lungs environment.

CARDIOVASCULAR DISEASES.

Moderate IHT protocol elicits beneficial cardiovascular effects Specifically, there is evidence IHT conditioning is a safe and effective therapy for both the prevention and the treatment of systematic hypertension, while it is also a promising therapeutic strategy in a myocardial infraction.

COGNITIVE | GERIATRIC

IHT has been proved to be an easy and safe therapy that improves cognitive performance and functional exercise capacity in gerlatric patients.

Considering the effect of the therapy on mitochondria, IHT promises to offer a higher quality of life to the silver generation.

WEIGHT MANAGEMENT I METABOLIC DISORDER

In metabolic syndrome the metabolic hormones alter, leading to increased food intake, obesity, hypertension and Insulin resistance. IHT protocols have been shown to have a beneficial effect on metabolism including reduction of body weight, cholesterol and blood sugar levels.

BORRELIOSIS

Millions of people are bitten by ticks every year.

A lot of clinics are using IHT as part of the chronic borrellosis treatment. Evidence suggests that Borrellas living in a human body can die after some weeks of HT sessions, due to their sensitivity to sudden oxygen concentration changes.

STRESS MANAGEMENT | BURNOUT

Mitochondrial disorders have been directly associated with chronic fatigue and also identified as coexisting conditions in patients diagnosed with burnout. IHT regenerates the mitochondria and therefore, offers a non-pharmacological option for treating conditions that influence not only the individual suffering from it but also the socioeconomic prosperity of the community.

PULMONARY DISEASES

One of the most striking therapeutic perspectives of IHT is its application in respiratory insufficiencies: It can be used as a therapeutic tool to restore lost respiratory motor output in severe clinical disorders such as amyotrophic lateral sclerosis, spinal cord injury, apnea and chronic obstructive pulmonary disease (COPD).

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